The 7 Best Women’s Shoes for Neuropathy [2021 Reviews]

Find a shoe to help your neuropathy, we break down this year's top models

Our Editors independently research, test, and rate what we feel are the best products. We use affiliate links and may receive a small commission on purchases.

Neuropathy can be incredibly bothersome, if not downright painful. Often causing weakness, tingling, numbness, and even burning sensations, it can seriously make you want to avoid walking or running around.

However, we have some great news: there are shoes out there that can help! We have taken our own experiences along with those from countless people suffering from neuropathy to bring you the best shoes for neuropathy on Amazon.

These range widely in style, functionality, and budget to ensure that there’s at least one pair just right for you.

Best Women’s Shoes For Neuropathy

 Orthofeet Orthopedic Walking ShoesGravity Defyer Mighty WalkVIONIC Footware Walker
Uppers:Synthetic fabricSynthetic fabric & leatherLeather
Sizes:5 - 12 X-Wide6 - 11 X-Wide5 - 13
Other:Arch support, roomy toe boxVersoShock Spring SystemEVA footbed, Active Motion System

For more of my running gear recommendations, have a look through these popular Women’s Workout guide links: Running Jackets, Running Shorts, Running Leggings.

Quick Answer: The 7 Best Rated Women’s Shoes Neuropathy

  1. Orthofeet Proven Orthopedic Walking Shoes
  2. Gravity Defyer Proven Pain Relief G-Defy Mighty Walk
  3. VIONIC Women’s Walker
  4. ASICS Women’s Gel-Venture 7 Running Shoes
  5. Ryka Women’s Devotion Plus 2
  6. Easy Spirit Women’s Romy Sneaker
  7. New Balance Women’s 411 V2 Walking Shoe

Our reviews to the top rated shoes for neuropathy with our comparison table and buyers guide will help you choose the right shoes for you.

Shoes for Neuropathy Reviews

Orthofeet Proven Orthopedic Walking Shoes at a Glance:

  • Uppers: Synthetic fabric
  • Sizes: 5 – 12 X-Wide
  • Colors: 1
  • Other: Anatomical arch support, roomy toe box

Let’s start things off with the model often considered to be the best shoes for diabetics with neuropathy: the Orthofeet Women’s Sneakers.

Coming in a single gray/white color scheme, they’re designed to be worn with just about every outfit without looking odd or out of place.

With comfort guaranteed, you’ll be able to try them out for 60 days and get your money back if you don’t feel great – no risks involved!

Keep in mind that these aren’t solely for diabetics with neuropathy. If you suffer from plantar fasciitis, heel pain, or overall foot pain, these are for you.

They’re incredibly lightweight, ensuring you feel light on your feet and don’t feel like they’re lugging you down.

Their ergonomic design features orthotic insoles, anatomical arch support, and amazing cushioning with multiple layers. Ultimately, it offers excellent support and will have you feeling like you’re walking on clouds.

As you know, our feet are the start of how the rest of our body feels while walking or running. That means if your feet are comfortable, it’ll take stress and pain off of your back, knees, hips, and even your neck!

If you have bunions or simply find regular shoes are too tight for your comfort, they even come in extended widths to offer the perfect fit and increase stability. Even the toe box is nice and roomy so you don’t feel any numbness due to squeezing and restriction!

The smooth interior lining helps wick sweat and excess heat away which is perfect for sensitive feet. Coming with extra foam padding, you don’t have to be bothered by chafing anymore either.

Gravity Defyer Proven Pain Relief Women’s G-Defy Mighty Walk at a Glance:

  • Uppers: Fabric and synthetic materials
  • Sizes: 6 – 11 X-Wide
  • Colors: 8
  • Other: VersoShock Spring System

Next up, we have the Gravity Defyer G-Defy Mighty Walk, which is one of the best shoes for peripheral neuropathy.

Coming in 8 different trendy colorways, you’ll be able to choose from schemes like light pink/gray, grey aqua, black/green, and many more.

They’re perfect for going to the gym, running errands, just hanging out, and everything in between!

Made of fabric and synthetic materials, the uppers are designed to be soft and airy. This allows for air to move in and out, while excess heat and moisture are moved away from the foot to keep them cool and dry at all times.

The seamless interior greatly reduces the change of chafing, blisters, and overall discomfort which is perfect for sensitive feet.

Removable insoles are nice and cushy, though you can replace them with your custom orthotics, should you prefer.

The front rocker sole comes with a supported midfoot which those suffering from plantar fasciitis are going to love, helping relieve pain and stress in this area of the foot. If you have bunions or just need extra room, the toe box is wide and extra deep.

Finally, the VersoShock Technology finished it all off nicely. This system is patented to absorb shock from the ground, converting it into energy. This will give you a bit more spring in your step instead of feeing like you’re carrying shoes made of concrete around.

VIONIC Women’s Walker at a Glance:

  • Uppers: Leather
  • Sizes: 5 – 13
  • Colors: 10
  • Other: EVA footbed, Active Motion System

The VIONIC Women’s Walker is yet another excellent choice if you want a good, comfy “every day” shoe. This model comes with everything you need to stay feeling great, even after hours of walking or standing on your feet.

Coming in 10 neutral colorways, they’ve been known to be great for healthcare workers and even restaurant workers who oftentimes require white or black footwear.

Made of either leather or suede, the uppers are incredibly durable, thus furthering how well they perform in workplace environments.

They do an excellent job at protecting the feet from liquids and bumps which could really hurt delicate feet.

A removable textile-covered EVA footbed is incredibly light but offers comfort and a nice amount of support. Along with that comes the Active Motion System which helps stabilize overpronators for ideal gait efficiency.

If you’d like to run in these, you can even do that too. The outsole is made for it, offering incredible durability and resistance, with a .5” elevation for smooth transitions each step you make.

Having received the American Podiatric Medical Association (APMA) Seal of Acceptance, it’s no surprise it’s considered to be the best shoes for neuropathy feet.

ASICS Women’s Gel-Venture 7 Running Shoes at a Glance:

  • Uppers: Synthetic fabric & leather
  • Sizes: 5 – 12 W
  • Colors: 18
  • Other: Stabilizing heel counter, ORTHOLITE Sockliner

Are you on the hunt for the best running shoes for neuropathy? Then you’re in the right place, because that’s exactly what you get with the ASICS Women’s Gel-Venture 7 Running Shoes.

ASICS is one of the most well-respected brands in the world due to their consistent quality, comfort, and style and you’ll find all of that in this model.

Coming in 18 different color schemes, you get quite a few options when it comes to looks.

Overall, they offer quite unique colors which will make you stand out in all the right ways. However, if you just want a plain black pair, they have that, too.

Made of fabric and synthetic materials, the uppers offer the perfect balance of flexibility, breathability, and protection. Mesh is prevalent here to keep your feet cool and dry, though synthetic leather overlays help to provide structure and protection while running.

The fabric linings only help to keep moisture and heat away from the feet, which can really be uncomfortable during long runs or walks. If you have issues with balance, you’ll appreciate the stabilizing internal heel counter while gently helps move your feet into natural alignment.

The ORTHOLITE sockliner provides just the right amount of cushioning, forming to the shape of your feet to work with their individual shapes instead of against them. Put that together with their signature GEL technology in the rearfoot and you have an ultra-shock-absorbing machine!

No matter where you’re running, the rubber sole will stay resistant against debris and offer a certain level of adhesion to keep you steady on your feet – even on slippery or uneven surfaces.

Ryka Women’s Devotion Plus 2 at a Glance:

  • Uppers: Synthetic fabric
  • Sizes: 5 – 11 W
  • Colors: 24
  • Other: 1″ heel, Anatomical Precise Return insole

Are you someone who likes to walk or run? Then check out the Ryka Women’s Devotion Plus 2.

This shoe has been highly rated all across the board, though they’ve quickly become known as some of the best walking shoes for neuropathy due to the incredible amount of comfort and space they offer.

Ryka not only stands out due to its superior performance, but because of its unique style, too.

24 color options are available to you, with the option to choose from Navy/Teal, to Grey/Coral, to Black Flex and so many more.

Their 4-way signature gradient print somehow combines modernity with a bit of a retro feel that will look great on just about any age or suite any fashion taste.

Synthetic uppers are smooth and come with ample mesh for moisture to escape, however, they did prove to be a bit heavier than the others we’ve covered so far. Not to say they’re heavy in general, but it is something to keep in mind.

The 1” heel helps to provide smooth transitions whether you’re walking, jogging, or running. Made of synthetic materials, the soles are ideal for smooth surfaces like pavement, gym floors, tile, hardwood, and so on.

A lace-up front ensures a customized, secure fit each time so you don’t have to keep adjusting while working out. The Lycra-lined tongue and comfort collar are very well though-out, eliminating the risk of chafing or cutting into the skin.

A built-in cushion only adds on to the comfort level. To complete the shoe, you get an Anatomical Precise Return insole which helps offer extra arch and heel support, making it another great option for plantar fasciitis, too.

Easy Spirit Women’s Romy Sneaker at a Glance:

  • Uppers: Leather, Mesh
  • Sizes: 3 – 14
  • Colors: 30+
  • Other: Cushioned Foam Sockliner

If you’re on a tight budget, that doesn’t mean that you still can’t get yourself a pair of the best women’s shoes for neuropathy.

The Easy Spirit Women’s Romy Sneaker exemplifies that, offering an affordable pair that ensures all the comfort and support you need to keep healthy and feeling great.

Coming in dozens of different colors and patterns, we’re sure you’ll find something that fits even your wildest style preferences.

Depending on the color and pattern you choose, you’ll either get suede or leather uppers. Both are some of the most durable out there, so you can plan on using these for quite a long time.

However, we know that leather isn’t breathable at all, so they’ve add in conveniently-located strips of mesh along the sides of the shoe to allow air to flow in and out.

The rubber soles are about 0.5” thick to allow for a smooth transition and more even gait so you expend energy during workouts – not just walking around running errands or working. The rubber is also tough, helping to absorb shock and transfer this energy well.

We enjoyed how flexible the sole was, working with our feet’s natural movement well. The padded collar and cushioned foam sock liners felt ultra-lux and even when we arrived home we were hesitant to take them off due to how comfy they were!

New Balance Women’s 411 V2 Walking Shoe at a Glance:

  • Uppers: Leather
  • Sizes: 5 – 12 W
  • Colors: 1
  • Other: Very durable

Last but not least are the best sneakers for neuropathy: the New Balance Women’s 411 V2 Lace-Up Walking Shoe.

New Balance is one of the most successful footwear brands in the world, known for their ingenious engineering that’s made to not only look great, but feel great.

Your feet will be in the lap of luxury while receiving some of the best support possible.

Coming in just white, they look very sleek and are perfect for casual environments just as well as many workplace situations.

The white will go with literally any color out there, so you don’t have to worry about them clashing. Made of leather, the uppers are soft, pliable, and over time, work to form to the individual shape of your feet.

If you have bunions, you’ll love the extra space you get, eliminating the restriction that “regular” sneakers can inflict.

While leather itself is not breathable, you do get little air holes around the shoes which look minimal and overall provide a clean, uniform appearance while helping to keep your feet dry and well-ventilated from the time you put them on until the time you take them off.

The rubber soles are tough and resistant to many scuffs to keep them looking brand-new. Not only that, but they absorb shock very well to greatly reduce the amount of fatigue you feel while walking.

Finally, lace-up closures will give you the best fit possible: never too tight nor too loose.

Women’s Neuropathy Shoes Comparison Table

Shoes For Neuropathy UppersSizesColorsOtherRating
Orthofeet Proven Orthopedic Walking ShoesSynthetic fabric5 - 12 X-Wide1Anatomical arch support, roomy toe box4.2 / 5.0
Gravity Defyer Mighty WalkSynthetic fabric & leather6 - 11 X-Wide8VersoShock Spring System4.2 / 5.0
VIONIC Footware WalkerLeather5 - 1310EVA footbed, Active Motion System4.2 / 5.0
ASICS Gel-Venture 7 Running ShoesSynthetic fabric & leather5 - 12 W18Stabilizing heel counter, ORTHOLITE Sockliner4.5 / 5.0
Ryka Devotion Plus 2Synthetic fabric5 - 11 W241" heel, Anatomical Precise Return insole4.4 / 5.0
Easy Spirit Romy SneakerLeather, Mesh3 - 1430+Cushioned Foam Sockliner4.6 / 5.0
New Balance 411 V2 ShoeLeather5 - 12 W1Very durable4.5 / 5.0

How to Choose the Best Shoes for Neuropathy – Buying Guide

Best Women’s Shoes For Neuropathy

Now that you’ve been able to read all about the good shoes for neuropathy, have you decided which pair is just right for you and your feet? If you aren’t quite decided yet, there’s no need to worry.

We know how difficult it can be to choose just one, especially when there are so many great options out there!

We’ve decided to go ahead and write up this user-friendly buying guide below to make sure that by the time you’re done reading, there will be no doubt which shoes are perfect for your needs!


First off, think about the kind of style you’re going for! Do you like the more low-profile, meshy-looking running shoes? Perhaps you like those that offer more thickness and padding for more protection.

Whatever your style is, there’s something on this guide to fit into it. Neuropathy shoes don’t have just one style, so it’s important you look at your tastes first. If you don’t like how they look, you’re just not going to wear them. It’s as simple as that.


Leather is one of the most common upper materials found in this category, though you also get a lot of mesh and synthetic materials. The upside of leather is that it’s incredibly durable and will likely last you for years of regular use.

Leather is also known to form to the shape of your unique feet over time, which further create a customized fit that will feel amazing. However, there are many people who are morally against wearing leather.

In this case, you have synthetic, fabric, and mesh materials. Mesh is nice and airy though you probably don’t want uppers that are just mesh, alone.

You need a bit of protection so make sure they also have overlays on the mesh. Fabric can be breathable and stretchy as well so as to never restrict your feet too much. Not only that, but they tend to be more lightweight than leather, as well as more affordable.


The soles on just about every shoe on our guide is made of rubber. Rubber is inexpensive, durable, and offers enough bounciness that it absorbs impact very well and transfers this energy back to you. This can make a huge difference in how you feel at the end of the day.

Soles not made of rubber could cause fatigue and make you feel like you have to lug your shoes around. If you’re planning on using them for at least a couple of hours per day, you’ll seriously notice a difference.


Support and cushioning are both essential to any good running or walking shoe, but more so when it comes to shoes for neuropathy. You ideally want support and cushioning in the midsole, heel, and forefoot but that’s not always possible.

The midsole is the most important of the bunch, though. EVA midsoles are one of the best, as they provide support yet are incredibly lightweight so they won’t weigh you down and create more fatigue.

Adding onto that, if you want to use your own orthotic inserts, make sure your insoles are removable to accommodate them.


Aside from looking at the overall material the uppers are made out of, make sure they have air holes or mesh incorporated as well. Look at the lining of the interior, as this will greatly affect the comfort level of those with sensitive feet.

Soft, moisture-wicking linings are the best as they’ll move excess heat and moisture away from your feet to keep them cool and dry.


Make sure that you’re also taking a look at the fit of the shoe as it doesn’t matter if you get the “best” neuropathy shoe out there if it doesn’t fit you correctly.

If you have bunions or simply need extra width, the vast majority of shoes on our guide come with Wide and even Extra-Wide sizing to help accommodate them and ensure you are as comfortable as you can be.


How much are you comfortable with spending on a pair of the best sneakers for neuropathy? We highly encourage you to set a budget for yourself before you start shopping, as it’s all too easy to spend more than you wanted once you come across a pair of shoes you really like.

Trust us when we say, that no matter what kind of budget you have, there is at least one pair out there that will fit into it. Don’t think that “expensive is better” as this isn’t always the case.

FAQs About Womens Shoes for Neuropathy

Q: What shoes should I wear for neuropathy?

A: Any of the models on our guide would work well for you. You want to look out particularly for extra cushioning and support throughout the length of the foot, with extra focus on the midsole. Thicker soles are helpful to provide extra cushioning and impact absorption as well.

Q: What helps foot neuropathy?

A: There are a ton of things that can help neuropathy, but it all comes down to what the source is. In many cases, it could be due to vitamin deficiencies. Exercise and essential oils have been proven to help, along with warm baths/soaks, and quitting smoking.

Q: Do compression socks help with neuropathy?

A: Compression socks have been shown to with many users, though it’s not a rule. It also depends on how advanced your neuropathy is.

Q: Can exercise reverse neuropathy?

A: It absolutely can! Cardio exercise can help if the right shoes are worn, though many strength training exercises have also been shown to help reduce symptoms of neuropathy.

Tips For Choosing Shoes for Neuropathy

#1: If you always wear orthotic inserts or wear them frequently, make sure the insoles of your new shoes are removable.

If not, you’re either going to have to rip them out which isn’t a good look, or use them on top of the insoles which is not going to be very secure nor provide you with the best fit and stability.

#2: Ensure that the closure will be tight enough for you but not too tight.

This is why we prefer laces for shoes for neuropathy. Laces can be adjusted to be tighter or looser depending on each of your feet, times throughout the day, and so on. When we exercise or stand on our feet for a long time, they tend to swell up. In these cases, having laces is crucial, where you can loosen them as you need.

#3: Look for cushioning not only under the foot, but around it as well.

We all know how sensitive our feet can get with neuropathy. Sometimes, even the smallest irritation can bring upon serious pain and discomfort. That’s why it’s important to look for cushioning around the collar and even around the tongue and interior – depending on your foot’s width.


We hope that you’ve been able to select the best sneakers for neuropathy for your individual needs and feet. We know that everyone is different, but by reading through you should now have a deeper understanding of what to look for and what you should be avoiding.

No matter what though, by selecting any of the aforementioned models you’ll be receiving some great neuropathy shoes for this condition. We hope that this guide has been able to narrow it down to just one. Thanks for tuning in, and we’ll see you again shortly!

How We Researched

To come up with the top women’s shoes for neuropathy, we researched a variety of sources for reviews such as REI, Walmart, Target and Dick’s Sporting Goods along with our own personal experience.

The authors consulted sources such as online magazines for research and reviews unbiased information.

By using we tried to eliminate fake reviews and use only genuine ones.

With so many options available, the authors narrowed down the selections by using products they felt were the best value for the money.

The staff authors have a wide and varied background as fitness trainers, yoga instructors and runners. The authors have decades of experience and are eager to share their knowledge with readers.

In order to narrow down the options, we used personal experiences plus recommendations from other trainers and instructors.



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Shayanne Weeks

Shayanne is a freelance writer and personal trainer based in LA, California. Describing herself as a nomad, she has lived in Boise, Idaho and Seattle, Washington as well as Guadalajara, Mexico. As an extremely active person, she loves to train people, teach yoga, and ski. She enjoys sharing her love for teaching others through her “how to” fitness guides and workout equipment reviews. Shayanne is addicted to surfing and yoga and practices both everyday.
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